Transcriptional Regulation of CRD-BP by c-myc: Implications for c-myc Functions
نویسندگان
چکیده
منابع مشابه
CRD-BP shields c-myc and MDR-1 RNA from endonucleolytic attack by a mammalian endoribonuclease
The c-myc mRNA coding region determinant-binding protein (CRD-BP) has high affinity for the coding region determinant (CRD) of c-myc mRNA. Such affinity is believed to protect c-myc CRD from endonucleolytic attack. We have recently purified a mammalian endoribonuclease which can cleave within the c-myc CRD in vitro. The availability of this purified endonuclease has made it possible to directly...
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ژورنال
عنوان ژورنال: Genes & Cancer
سال: 2010
ISSN: 1947-6019,1947-6027
DOI: 10.1177/1947601910395581